Molecular Biology of the Cell （5th edition）大细胞 （第五版）9780815341062 Packaged with a Media DVD-ROM 网盘下载 pdf 免费 2025 在线 epub 电子版

For nearly a quarter century Molecular Biology of the Cell has been the leading cell biology textbook. This tradition continues with the new Fifth Edition, which has been completely revised and updated to describe our current, rapidly advancing understanding of cell biology. To list but a few examples, a large amount of new material is presented on epigenetics; stem cells; RNAi; comparative genomics; the latest cancer therapies; apoptosis (now its own separate chapter); and cell cycle control and the mechanics of M phase (now integrated into one chapter).

The hallmark features of Molecular Biology of the Cell have been retained, such as its consistent and comprehensive art program, clear concept headings, and succinct section summaries. Additionally, in response to extensive feedback from readers, the Fifth Edition now includes several new features.

It is now more portable. Chapters 1-20 are printed and Chapters 21-25, covering multicellular systems, are provided as pdf files on the free Media DVD-ROM which accompanies the book.* And for the first time, Molecular Biology of the Cell now contains end-of-chapter questions. These problems, written by John Wilson and Tim Hunt, emphasize a quantitative approach and the art of reasoning from experiments, and -they will help students review and extend their knowledge derived from reading the textbook. The Media DVD-ROM, which is packaged with every copy of the book, contains PowerPoint® presentations with all of the figures, tables and micrographs from the text (available as JPEGs too). Also included is the Media Player, which plays over 125 movies—animations, videos, and molecular models—all with voiceover narration. A new reader-friendly feature is the integration of media codes throughout the text that link directly to relevant videos and animations. The Media DVD-ROM holds the multicellular systems chapters (21-25) of the text as well.

By skillfully extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and thereby create a coherent framework through which readers may approach and enjoy this subject that is so central to all of biology.

* There is also a reference edition of Molecular Biology of the Cell, Fifth Edition (ISBN 978-0-8153-4111-6) that contains Chapters 1-25 entirely in printed format.

About the Author

Bruce Alberts received his Ph.D. from Harvard University and is Professor of Biochemistry and Biophysics at the University of California, San Francisco. For 12 years, he served as President of the U.S. National Academy of Sciences (1993-2005).

Alexander Johnson received his Ph.D. from Harvard University and is Professor of Microbiology and Immunology and Director of the Biochemistry, Cell Biology, Genetics, and Developmental Biology Graduate Program at the University of California, San Francisco.

Julian Lewis received his D.Phil. from the University of Oxford and is a Principal Scientist at the London Research Institute of Cancer Research UK.

Martin Raff received his M.D. from McGill University and is at the Medical Research Council Laboratory for Molecular Cell Biology and the Biology Department at University College London.

Keith Roberts received his Ph.D. from the University of Cambridge and is Emeritus Fellow at the John Innes Centre, Norwich.

Peter Walter received his Ph.D. from The Rockefeller University in New York and is Professor and Chairman of the Department of Biochemistry and Biophysics at the University of California, San Francisco, and an Investigator of the Howard Hughes Medical Institute.

Special Features

Detailed Contents

Acknowledgments

A Note to the Reader

PART I　INTRODUCTION TO THE CELL

1.　Cells and Genomes

2.　Cell Chemistry and Biosynthesis

3.　Proteins

PART II　BASIC GENETIC MECHANISMS

4.　DNA, Chromosomes, and Genomes

5.　DNA Replication, Repair, and Recombination

6.　How Cells Read the Genome: From DNA to Protein

7.　Control of Gene Expression

PART III　METHODS

8.　Manipulating Proteins, DNA, and RNA

9.　Visualizing Cells

PART IV　INTERNAL ORGANIZATION OF THE CELL

10.　Membrane Structure

11.　Membrane Transport of Small Molecules and the Electrical

　Properties of Membranes

12.　Intracellular Compartments and Protein Sorting

13.　Intracellular Vesicular Traffic

14.　Energy Conversion: Mitochondria and Chloroplasts,

15.　Mechanisms of Cell Communication

16.　The Cytoskeleton

17.　The Cell Cycle

18.　Apoptosis

PART V　CELLS IN THEIR SOCIAL CONTEXT

19.　Cell Junctions, Cell Adhesion, and the Extracellular Matrix

20.　Cancer

21.　Sexual Reproduction: Meiosis, Germ Cells, and Fertilization

22.　Development of Multicellular Organisms

23.　Specialized Tissues, Stem Cells, and Tissue Renewal

24.　Pathogens, Infection, and Innate Immunity

25.　The Adaptive Immune System

Glossary

Index

Tables　The Genetic Code, Amino Acids

目次:

部分：细胞导论

1．细胞和基因组

2．细胞化学和生物合成

3．蛋白质

第二部分：基础基因结构

4．DNA, 染色体和基因组

5．DNA复制，修补和重新组合

6．细胞如何解读基因组：从DNA到蛋白质

7．基因表达控制

第三部分：方法

8．利用蛋白质，DNA 和RNA

9．肉眼可视细胞

第四部分：细胞内部组织

10.薄膜结构

11.小分子膜转运和膜电学特性

12.细胞内间隔和蛋白质筛选

13.细胞内小泡运输

14.能量转化，线粒体和叶绿体

15.细胞间传达机制

16.细胞框架

17.细胞周期

18.细胞凋亡

第五部分：群居环境中的细胞

19. 细胞连接，细胞粘连和细胞外矩阵

20. 肿瘤

1-20章是纸本形式，21-25章涉及多细胞系统，无纸本形式，内容包含在随书附送的DVD-ROM 光盘中

21. 有性生殖：减数分裂，生殖细胞和授精

22. 多细胞机体的发展

23. 特殊组织，干细胞和组织恢复

24. 病原体，传染病和先天免疫

25. 适应性免疫系统

Bruce Alberts，哈佛大学Ph.D.，加利福尼亚大学生物化学与生物物理学教授，《科学》杂志主编，前美国科学院主席（1993-2005）

Dennis Bray，麻省理工学院Ph.D.，剑桥大学名誉教授，2006年微软欧洲科学奖得主

Karen Hopkin，阿尔伯特•爱因斯坦医学院生物化学Ph.D.，科

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编辑推荐

该书被称为细胞分子生物学领域的圣经，出版至今，国内销量超过1300册

课程分类：细胞生物学

适合年级：本科高年级、研究生

《细胞分子生物学，第五版》将延续其作为细胞生物学教材的领先地位，第5版进行了全面的修订，增加及时更新的内容与资料，充分反映了当前细胞生物学飞速发展的现状。

新版在保留前几版内容全面、连贯，概念清晰，归纳简洁等优点的基础上，广泛采纳读者的反馈和建议，做了进一步的完善和改进，特点主要包括：

更加便携

纸本书中收录1-20章的内容，21-25章（包括多细胞系统）以 PDF文件形式收录在随书附送的DVD-ROM光盘中。

1-20章附有习题

习题部分由John Wilson 和 Tim Hunt编写，强调定量和实验分析，有助于学生更好地掌握和扩展所学知识

随书附送DVD-ROM光盘

光盘内容包括：PPT演示文稿（涵盖书中所有的数据，图像，表格及显微图）并配有解说的影音文件（包含125个动画、视频与分子模型文件）。关于多细胞系统的21-25章以PDF格式的文件出现在DVD中。

媒体码贯穿全书

通过媒体码可以直接链接到附送的DVD-ROM光盘中相对应的视频和动画，读者在电脑中输入书中出现的特定4位代码即可链接查看。.

课件内容丰富全面

包括视频，AVI格式的视频，PPT和JPG格式的数据图像，表格与图表，媒体指南, 习题库，讲稿提纲等。课件简学易用，供采纳该书作为教材的老师免费使用。

Throughout the book, emphasis is placed not just on what we know but also on how we know and what remains to be discovered- important for engaging and enthusing students....A quarter of a century after the first edition revolutionised cell biology textbooks, the new edition is as fresh, comprehensive and above all, as readable as ever....Like its predecessors, this is a superb textbook for advanced undergraduate and postgraduate students.

Professors, lecturers, and instructors will find the fifth edition of the book Molecular Biology of the Cell and its accompanying Problems Book to be an excellent choice for guiding their students through the maze of the cells molecular structures and biochemical processes....With countless colorful illustrations and a large number of photographs and tables, reading the text becomes not only an educational experience, but also a highly enjoyable one for those students who wish to discover the inner workings of the magnificent cellular machine....Educators will also find the DVD-ROM to be a rich electronic resource when compiling their lectures....No less important is the Problems Book, which contains numerous exercises and questions that are an integral part of the learning process, and that teachers, instructors, and students are sure to appreciate.

书籍介绍

在线阅读本书

For nearly a quarter century "Molecular Biology of the Cell" has been the leading cell biology textbook. This tradition continues with the new Fifth Edition, which has been completely revised and updated to describe our current, rapidly advancing understanding of cell biology. To list but a few examples, a large amount of new material is presented on epigenetics; stem cells; RNAi; comparative genomics; the latest cancer therapies; apoptosis (now its own separate chapter); and cell cycle control and the mechanics of M phase (now integrated into one chapter). The hallmark features of "Molecular Biology of the Cell" have been retained, such as its consistent and comprehensive art program, clear concept headings, and succinct section summaries.Additionally, in response to extensive feedback from readers, the Fifth Edition now includes several new features. It is now more portable. Chapters 1-20 are printed and Chapters 21-25, covering multicellular systems, are provided as pdf files on the free Media DVD-ROM which accompanies the book. And for the first time, "Molecular Biology of the Cell" now contains end-of-chapter questions. These problems, written by John Wilson and Tim Hunt, emphasize a quantitative approach and the art of reasoning from experiments, and - they will help students review and extend their knowledge derived from reading the textbook.The Media DVD-ROM, which is packaged with every copy of the book, contains PowerPoint[registered] presentations with all of the figures, tables and micrographs from the text (available as JPEGs too). Also included is the Media Player, which plays over 125 movies -animations, videos, and molecular models - all with voiceover narration. A new reader-friendly feature is the integration of media codes throughout the text that link directly to relevant videos and animations. The Media DVD-ROM holds the multicellular systems chapters (21-25) of the text as well. By skillfully extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and thereby create a coherent framework through which readers may approach and enjoy this subject that is so central to all of biology. There is also a reference edition of "Molecular Biology of the Cell, Fifth Edition" (ISBN 978-0-8153-4111-6) that contains Chapters 1-25 entirely in printed format.